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As the primary organ responsible for steroid metabolism, the liver is particularly susceptible to the toxic effects of 17--alkylated oral anabolicandrogenic steroids, such as stanozolol and methyltestosterone ( Mechanistic studies suggest that anabolicandrogenic steroids impair mitochondrial -oxidation and deplete intracellular glutathione stores, resulting in lipid peroxidation and activation of apoptotic signalling pathways

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Editing by Joyjeet Das)

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Trace Minerals Research [Internet] [accessed 12 Feb 18] Available at Pizzino G, et al

Aging (Albany NY) 5 , 288303, doi:10.18632/aging.v5i4 (2013)