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Translating these findings into effective therapies for OP, OA, and OS presents numerous challenges

Update on facial erythema in rosacea

Sample type considerations Different biological matrices have different detection characteristics: Urine: Most common testing matrix, metabolites accumulate Blood/plasma: Shorter detection windows for most peptides Dried blood spots: Emerging method with good sensitivity Hair: Not commonly used for peptides but theoretically possible Most anti-doping testing uses urine

Methionine, cysteine, histidine, tryptophan, and tyrosine are most susceptible to oxidation: Met and Cys because of their sulfur atoms and His, Trp, and Tyr because of their aromatic rings (6)

137 The mild anemia caused by its administration is rapidly corrected by a compensatory erythropoietic effort and does not recur unless the dose of drug is escalated

Lab Invest 80 , 735744 (2000)