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Additionally, extreme values in the dataset were removed when identified as outliers through Grubbs method

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More subcutaneous fat means a longer needle is needed to reach muscle reliably

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*Correspondence: Ming Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Berberine inhibits the nuclear translocation of -catenin and the expression of target genes such as cyclin D1 and VEGF by downregulating Trx1, and simultaneously inhibits MAPK1 (ERK1/2) phosphorylation and NOX4-mediated ROS production, thereby blocking the metabolic reprogramming of abnormal PASMC proliferation (Yu et al., 2020