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Interestingly, inactivating mutations in URAT1 have been shown to cause renal hypouricemia

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It was discovered to have anti-pigment properties through multiple pathways

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To clarify the specific role of IGF-1 on MSC function, in the current study, we further investigated the role of IGF-1 in MSCs during osteoblast differentiation using conditional knockout of IGF1R in the Nestin + MSCs

Underlying mechanisms of tinnitus: Review and clinical implications