Under PCAC review since October 2024
Newer formulations like liposomal glutathione or sublingual (under-the-tongue) routes can improve absorption somewhat, but they still cant match the direct delivery of an IV
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Ipamorelin, on the other hand, is a selective GHRP (Growth Hormone Releasing Peptide) that acts on ghrelin receptors, amplifying GH release in a controlled, physiological pattern
Developed by Theratechnologies Inc., it underwent phase II trials in the mid-2000s for GH deficiency (GHD) and HIV lipodystrophy but was discontinued, with reported reasons including hypersensitivity reactions, including an anaphylaxis-like reaction in one trial participant Wong et al (2008) [Note: Abstract only
It does this gently and specifically, without disrupting other hormones