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95% CI, 0.740.91)

The first is liraglutide, which is sold under the name Saxenda

With or without food

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that works through several mechanisms to improve glycemic control and, in higher doses, promote weight loss

Chromatin assembly factor 1 (CAF-1) is a protein that deposits histones onto newly replicated DNA in silenced regions of the genome

Its strong brand recognition and established prescriber comfort have made it the initial therapy of choice for many patients and healthcare providers initiating pharmacotherapy for obesity, thereby driving the majority of volume through home delivery channels as patients establish long-term treatment routines