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First-in-human evaluation of oral denatonium acetate (ARD-101), a potential bitter taste receptor agonist: a randomized, double-blind, placebo-controlled phase 1 trial in healthy adults

In the realm of cardiometabolic diseases, P.g promotes atherosclerosis by altering gut microbiota to upregulate bacterial carbohydrate metabolism proteins and reduce serum HDL (Park et al., 2023)

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Answer: As with any medication, these are to be expected

10.1053/jpsu.2001.20690 17 BaiS.ZhangM.TangS.LiM.WuR.WanS.et al (2024)