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Trial evidence describes averages across populations, not guarantees for an individual, and the labels that govern weight-management use are specific to particular brands

This makes oral administration viable, particularly for gastrointestinal applications where the peptide can act locally on the gut lining

doi: 10.1016/j.mce.2015.02.014

Conversely, data from clinical trials have showed an increased risk of incident heart failure with DPP4 inhibitors compared to placebo

Most Common Side Effects of GLP-1 Medications Like any medication, GLP-1 treatments come with side effects, most of which are mild, temporary, and tend to improve as your body adjusts

Your healthcare provider might also suggest adjustments to your medication or other treatments to help manage this side effect