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Because PT-141 does not rely on vascular dilation, its effectiveness is not dependent on blood flow

doi: 10.1007/s00125-010-1876-8

Miyauchi T, Yamada M, Yamamoto A, Iwasa F, Suzawa T, Kamijo R, Baba K, Ogawa T

Generally, the sensitivity of a reaction to substituent effects ( ) increases with decreasing solvent polarity and solvent Lewis basicity

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