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Taking niacin in large amounts can also cause liver damage, which can be very serious

Most side effects are mild and transient, such as temporary injection site discomfort or minor bruising that resolves within 2448 hours

The absolute risk increase for diabetic retinopathy complications was larger among patients with a history of diabetic retinopathy at baseline (semaglutide injection 8.2%, placebo 5.2%) than among patients without a known history of diabetic retinopathy (semaglutide injection 0.7%, placebo 0.4%)

1. Metabolic Regulation (Fat Loss)

The most commonly reported adverse events in Phase 2 and Phase 3 trials were gastrointestinal in nature, including nausea, diarrhea, vomiting, and constipation

Of note, the research on KPVs effects has been done primarily in animal models and human cell cultures, not in human subjects directly