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While the objective response rate and DCR are mostly higher in those who develop irAEs, the OS and PFS data are dependent on the tumour type, degree of toxicities, affected spectrum of system/organs and inherent patient characteristics

More concerning reactions requiring immediate medical attention include severe persistent abdominal pain potentially indicating pancreatitis, symptoms of allergic reactions including rash, itching, or difficulty breathing, or signs of hypoglycemia such as excessive sweating, confusion, or rapid heartbeat

Verify documentation completeness and batch number consistency

Funding for the study came from the National Institutes of Health (grants GM63879, HL107904, HL109442, HL133191, DE023105, and AR066101).

It belongs to a plant family called Malvaceae and is rich in fibre and important nutrients

4 Slower transit through the entire GI tract means more time for water reabsorption, which can lead to constipation and hard stools