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Stress-induced gene expression and behavior are controlled by DNA methylation and methyl donor availability in the dentate gyrus
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Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism
Glutathione is a molecule made in the liver from three amino acids: glutamine, glycine, and cysteine
CHCHD2 mutations can trigger protein clumping in the intermembrane space of mitochondria (175), damaging the ETC, augmenting ROS, and leading to aberrant mitochondrial activity and dopaminergic neuron loss (176)
Pre-clinical and clinical studies are necessary to confirm the efficacy of these treatments and establish their role in glaucoma management
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