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A relatively new class of drugscalled sodium-glucose cotransporter-2 (SGLT2) inhibitorshave proven beneficial for both diabetic and non-diabetic CKD and appear poised to become a mainstay treatment

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Deuterated PUFAs and MUFAs can also inhibit ACSL4 by reducing PL-PUFAs

NICE guidance recommends 1 mg hydroxocobalamin three times weekly for 2 weeks for patients without neurological symptoms, with lifelong maintenance therapy for irreversible causes

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pH can drift outside the safe range