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Due to a risk of worsening psychosis, patients with a major psychotic disorder should not be treated with Rytary

Levin D, Bell S, Sund R, Hartikainen SA, Tuomilehto J, Pukkala E, Keskimaki I, Badrick E, Renehan AG, Buchan IE, Bowker SL, Minhas-Sandhu JK, Zafari Z, Marra C, Johnson JA, Stricker BH, Uitterlinden AG, Hofman A, Ruiter R, de Keyser CE, MacDonald TM, Wild SH, McKeigue PM, Colhoun HM

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Monotreme GLP-1 elicits a different signalling cascade compared to hGLP-1 when binding to the GLP-1 receptor Closer examination of potencies in receptor activation revealed differential signalling bias for monotreme GLP-1 peptides in comparison to that elicited by hGLP-1

doi: 10.1016/j.ssmph.2022.101106 6 KlinitzkeGSteinigJBlherMKerstingAWagnerB

This coating then acts as a framework for rebuilding the mineral structure of enamel