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10.1124/jpet.115.230391 J
However, it also has been found to be associated with insulin resistance syndrome including obesity, fat distribution, hypertension, dyslipidemia, and cardiovascular disease [48]
Current issues regarding treatment of mitochondrial fatty acid oxidation disorders
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For example, a 2005 study found that NAC administration failed to raise glutathione levels in rats,36 and a 2022 study on mice suggested that it may promote the metastatic spread of certain cancers.37 While its true that animal studies don't directly translate to human outcomes, they're still important to consider when choosing a supplement meant to support your health and wellness
As it stands, more mechanistic work is necessary to elucidate whether BA supplementation can lead to greater muscle carnosine gains above those shown with current recommendations
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