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Therefore, it is recommended to refrain from its use during the first 10 weeks of gestation, a period marked by heightened fetal susceptibility to teratogens ( Mycophenolate mofetil Avoidance of this medication is imperative during pregnancy due to its association with increased risks of first-trimester pregnancy loss and a heightened incidence of congenital malformations ( To mitigate these risks, it is recommended to discontinue mycophenolate at least 6 weeks before conception ( Methotrexate Administering methotrexate before and during pregnancy carries the potential for lasting consequences on fetal growth ( Leflunomide It is cautioned to be avoided during pregnancy based on the results of preclinical reproductive studies, although its definitive teratogenicity in humans remains uncertain

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Potential side effects of B12 injections are generally mild but should be monitored