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Common adverse effects include gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation), which typically improve over time

the similar GIP/GLP-1 medication, tirzepatide (Mounjaro, Zepbound)

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The pl of a peptide may be theoretically calculated from the pK values of its amino acids and of the terminal amine and carboxyl groups and can be used to predict the solubility of the peptide at a given pH

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Off-label use, misuse, patient expectations: As public demand surges, there is risk of overpromising, misuse (e.g