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The lower intracellular levels of serine and glycine in cancer cells that we observed in vitro indicate a high turnover with increased consumption and usage of these amino acids in downstream biosynthetic pathways, which is supported by the enhanced SHMT2 expression in response to RT

cerevisiae , ACT1 and UBC6 , were used as reference genes

L-Glutathione is generally safe within recommended doses, but long-term use can have side effects

AsGGT3-5-RACE-RT (5-[Phos]GTATC CATCGGGAAT-3), AsGGT3-5-RACE-F1 (5-TGAAAAAGAAA GGGCAGCTC-3), AsGGT3-5-RACE-F2 (5-GGTTTAGGGATT GCAAATGG-3), AsGGT3-5-RACE-R1 (5-CCTCCACTTGCGC CTAGAG-3), and AsGGT3-5-RACE-R2 (5-GGTGGCGGCATAT TGTTATT-3) for AsGGT3

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Later, a Science investigation raised suspicions, presenting evidence that Sylvain Lesn, a professor in UMN's Department of Neurology, who was Ashe's protg and the paper's first author, used manipulated data not only in the Nature paper but in other publications as well