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Molecules 24 , 4309 (2019)

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Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicin-treated human breast carcinoma cells

Healthy & Nourished Skin: L-Glutathione is a master antioxidant which supports body's defense against free radicals

Together, These results indicated PPARa alleviates ferroptosis primarily through reducing lipid-derived ROS rather than modulating GSH metabolism or PUFA synthesis