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Li S, Sheng ZJ (2022) Energy matters: presynaptic metabolism and the maintenance of synaptic transmission
Inhibition of NNMT has been shown to reduce fat accumulation and increase energy expenditure in preclinical models
Foods high in saturated fats may promote inflammation and slow gut healing
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In contrast, ferroptosis inhibition via iron chelation or lipid radical scavenges blocked this Hmox1 activation-induced cardiac damage, supporting a ferroptosis targeting therapeutic strategy to alleviate cardiomyopathy in SCD 46
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