Nutrition shifts: Favouring fibre-rich foods, limiting saturated fat load, and maintaining a modest energy deficit (around 500-1,000 kcal/day) can meaningfully reduce lipid-driven insulin resistance over time
Furthermore, a study on hepatocellular carcinoma reported that ID decreased ENPEP expression and promoted angiogenesis and metastasis through the transcription factor SP1, providing additional insight into how ID may enhance hepatocellular carcinoma progression (133)
Abbreviations: CV, coefficient of variation
Not yet in formal clinical trials
As a result, those patients with cardiovascular risk factors may prefer Ozempic over other weight loss medications
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