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It binds strongly to several melanocortin receptors

And it doesnt cause weight gain, is highly effective when taken consistently, doesnt cause hypoglycemia, and its relatively affordable. While the impact of metformin is significantly more subtle and gradual than that of GLP-1s, its still beneficial for almost anyone with diabetes, regardless of other medications

Important caveat: B12 injections are most effective when you have deficiency or suboptimal levels

The most effective strategies address both the timing of digestion and the microbial environment

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