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The quality of each included RCT was assessed by the Cochrane Risk-of-Bias Tool 1.0

Abbreviations ALL: Acute lymphoblastic leukemia Met: Metformin CQ : Chloroquine AraC : Cytarabine MDA : Malondialdehyde FRAP: Ferric reducing antioxidant ability DPPH: 2,2-Diphenyl-1-picrylhydrazyl allo-HSCT : Allogeneic hematopoietic stem cell transplantation CAR-T: Chimeric antigen receptor T-cell WHO: World Health Organization AMPK : Adenosine monophosphate-activated protein kinase HDF: Human dermal fibroblast FBS : Fetal bovine serum PBS: Phosphate-buffered saline FITC: Fluorescein isothiocyanate PI: Propidium iodide qRTPCR: Quantitative real-time polymerase chain reaction TAC: Total antioxidant capacity GSH: Reduced glutathione GSSG : Oxidized glutathione OD: Optical density DTT: Dithiothreitol HCQ : Hydroxychloroquine PARP: Poly ADPribose polymerase References Dander, E., Palmi, C., DAmico, G

It promotes cell migration, angiogenesis, anti-inflammatory regulation, and anti-apoptotic signaling, all critical for wound repair

Liberini, C

Diet and Amytorophic Lateral Sclerosis

Insomnia and dry mouth round out the less common but notable side effects