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Conversely, discontinuation rates were increased to 33.7% (95% CI 33.4, 34.0) at 1 year and 50.6% (95% CI 50.3, 50.9) at 3 years when using a grace period of 60 days (ESM Table 4)

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Its role in bone formation has been considered both within the realm of its role as a storage protein and as a potential agonist for IGF-I, although a receptor for IGFBP-5 has not been identified

This means you do not need to fast, wait before eating, or avoid coffee in the same way you do with Wegovy tablets