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Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell lines

The top 10 hub proteins ranked by node degree are summarized in (Figure 2H), highlighting critical intervention points in AD-related networks

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Preclinical and cell culture research has examined exogenous glutathione for its capacity to replenish intracellular GSH pools under oxidative stress conditions, modulating Nrf2/ARE pathway activity and mitochondrial redox balance