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In parallel, vectors consisting of adeno-associated viruses (AAV) provide a gene therapy-based approach for sustained, localized expression of neurotrophic factors in target brain regions [243, 244]

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Additional support was provided by the Japan Agency for Medical Research and Development (JP25ama221330), the Association Robert Debr pour la Recherche Mdicale, the AACR 2025 Career Development Award in Lung Cancer Research, the Prix Surs Lucie et Olga Fradiss 2025, the Fonds de recherche Qubec Sant, the Cancer Research Society, the Society of Immunotherapy of CancerMelanoma Research Alliance, AIRC (projects 32405 and 30203), the Ontario Institute of Cancer Research and the London Health Sciences Foundation

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