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By 50, grip strength, leg press capacity, and overall functional strength decline measurably (Cruz-Jentoft et al., Lancet, 2019)

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Tomio K, Kawana K, Taguchi A, Isobe Y, Iwamoto R, Yamashita A, et al

But it also requires more frequent dosing

The literature on fructose was published in The Lancet in 1970 saying that fructose consumption was related to gaining weight, higher blood pressure, and elevated blood sugar