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[If youre worried about potential harms,] you should discuss them with your physician.

Methods Islets were isolated from wild-type (WT), Gipr -knockout ( Gipr / ), Gcgr -knockout ( Gcgr / ), Glp-1r (also known as Glp1r )/ Gipr double-knockout and Trpm5 -knockout ( Trpm5 / ) mice, followed by assessment of beta cell function and insulin secretion in response to mono- and multi-agonist administration

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Conflict of interest The authors declare the following conflicts of interest: MS-R has received honoraria for presentations from HRA Pharma

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