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In a noncontrolled study of 20 patients that did not tolerate TADs and that were started on zonisamide (mean dose of 400mg/day) or levetiracetam (mean dose of 1,000mg/day), 75% had a moderate clinical response, whereas 20% had complete symptom remission.92 Topiramate, another anticonvulsive and antimigraine agent, can also be used as prophylactic treatment.93 It is usually started with 25mg per day and the dose is increased 25mg every week, until reaching 100mg per day

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