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This synergy helps GLP-1 patients achieve a healthier body composition by focusing on fat loss while maintaining or even gaining muscle mass

Joshua Silva, MD Nov 7, 2025 13 min read Updated: Apr 17 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD As GLP-1 and GLP-1/GIP medications such as semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) continue to transform medical weight management, one question comes up repeatedly: Do these medications cause muscle lossor even muscle wasting

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Gastrointestinal issues such as nausea and vomiting remain the most common side effects

Dizziness may occur when standing quickly, especially during rapid weight loss phases when blood pressure drops

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