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Wei Z, et al
As with other substance use disorders, both genetic (such as mutations in the opioid receptor gene (10)) and environmental factors (such as exposure to trauma), contribute to the risk of developing opioid use disorder.(11) Ready access to prescription opioid, heroin, and fentanyl have all contributed to the current opioid epidemic
The US Food and Drug Administration (FDA) has approved the oral formulation of the GLP-1 weight-loss drug Wegovy, making it the first oral GLP-1 therapy cleared for obesity treatment ahead of rival Eli Lillys orforglipron, which is still under FDA review
Cancer Res (2014) 74:357990
However, if you are pregnant, nursing, or have a specific medical condition (particularly related to the liver or kidneys), you should always consult with your physician before starting any new supplement regimen
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