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This balance influences numerous redox-regulated cellular processes, including the modulation of signaling pathways, post-translational modifications such as protein glutathionylation, activation of transcription factors like Nrf2 and NF-B, and the regulation of cell fate decisions such as proliferation or apoptosis [38]

When the cancer cells break out of latency, they reinitiate overt outgrowth and overtake the local tissue microenvironment