493 Firstly, NMNAT acts as a stress-response protein that aids the clearance or refolding of misfolded proteins like a chaperone
Effector functions that are triggered unequally by different nAbs but that are important for protection in vivo, or poor mimicry of in vivo neutralization by the in vitro assay, may be contributory factors
Both MT-I and MT-II appear to activate this receptor type, with MT-II appearing to be a much more potent activator [1, 10, 11]
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