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Limitations persist in the extant literature: data on the safety and efficacy of tirzepatide in type 1 diabetes are insufficient, and its neuroprotective mechanisms are not fully elucidated

As high-energy-demand cells, cerebral neurons require continuous bioenergetic supply to power neurotransmitter biosynthesis and vesicular secretion, action potential propagation, and synaptic plasticity modulation

doi: 10.1113/expphysiol.2006.034876

Stimulation of other MC receptors may lead to outcomes such as penile erection, sexual arousal, and appetite suppression

Overall, the sustained efficacy of GLP-1 injections makes them a valuable tool in combatting obesity

Without these supporting behaviors, a patient will likely regain weight when they reduce dosage or stop taking the drug