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GHK-Cu has been shown in research settings to modulate gene expression related to collagen synthesis, inflammation regulation, and tissue remodeling, making it a focal point in studies involving dermal and connective tissue models

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Resveratrol, as a SIRT1 agonist, can significantly upregulate the expressions of SIRT1, beclin 1 and LC3II/I, while down-regulating the expression of p62, thereby promoting the autophagic activity of HUVECs

10.1016/j.jamcollsurg.2010.09.020 311 WoolfN