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It is indicated as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity such as hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease

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Safety assessments included adverse events (AEs), hypoglycemic episodes, clinical laboratory assessments, vital signs, physical examination, and electrocardiogram

Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, Perfetti R

It works to block the receptor for interleukin 1-beta, an important inflammatory chemical (cytokine)

It is also often used to create liposomes , small spheres surrounded by phospholipid bi-layer designed to carry some active ingredient and help its absorption