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2006) A large cohort from the US Nurses Health Study of 83,076 female participants, which was followed over 24 years, observed a significant inverse association between coffee consumption and the incidence of stroke

Kopp MA, Liebscher T, Niedeggen A, Laufer S, Brommer B, Jungehulsing GJ, et al

It adds that providers should set out expected timelines, realistic efficacy ranges, and when to reassess if outcomes differ from expectations

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All samples were analyzed by Western blotting as indicated below