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Different diagnostic criteria and thresholds for the assessment of iron deficiency and IDA can lead to different prevalence estimates (172)

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Some biological effects shown by betanin are reduced in two redox-sensitive pathways, nuclear factor kappa B (NFkB) and nuclear factor erythroid-2-related factor (Nrf2)antioxidant response element (ARE) are the major transcription genes for inflammatory responses, and are detoxifying/antioxidant (184, 185)

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