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It is one of the first randomized controlled trials to explore the safety and effectiveness of semaglutide in patients with schizophrenia, obesity, and prediabetesconditions that commonly overlap due to the metabolic side effects of second-generation antipsychotics

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Age-related comorbidities (metabolic syndromes) such as, obesity, T2DM, asthma, and CVD, could also increase severity and mortality in elderly COVID-19 patients

Many patients with lung cancer are already at risk of cachexia an involuntary loss of muscle mass and body weight driven by the metabolic effects of cancer itself

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One focus of the recent research is into the long-term interaction of GIP and GLP-1 receptor signalling, which could potentially be clarified if a long-acting GIP receptor agonist, which has already been investigated in rodent studies [24,25], can also be studied in humans