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Its main metabolite, DM-6705 (M1), accounts for 13%18% of total plasma exposure and has been associated with QT prolongation

GLP-1 RAs showed trends toward improvements in endocrine and metabolic, cardiovascular, renal, and respiratory outcomes, cognitive function, with a potential reduction in fracture risk and all-cause mortality in certain populations

doi: 10.3748/wjg.v24.i27.2974

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