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Clinical evidence suggests omeprazole has minimal impact on GLP-1 medication effectiveness in most patients, though individual variation exists

Due to the detrimental effects of all constituent elements of MetS on the endothelium, it is plausible that endothelial dysfunction is more prevalent among individuals with MetS

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Semaglutide activates only GLP-1 receptors, while tirzepatide is a dual agonist that also activates GIP receptors, typically producing slightly higher weight loss in trials

Results Patient demographics To study perioperative GLP-1 and GLP-2 plasma concentration dynamics, we included 46 patients, undergoing minor (n = 26) or major (n = 20) hepatic resections