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The macrovesicular and the microvesicular fatty change (vacuolation) generally located at the cell periphery stains positively for Oil Red-O and the membranes surrounding these lipid vacuoles stain positively for adipophilin (a protein that forms the membrane around non-lysosomal lipid droplets) but negative for LAMP-2 (a lysosome-associated protein) by immunohistochemical techniques (Obert et al
They reduce hydrogen peroxide and organic hydroperoxides to water or alcohols by oxidizing GSH to GSSG
However, consistent nutrition remains important, particularly for individuals whose anticoagulation therapy is sensitive to vitamin K intake
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