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Further, other NOX2-mediated H 2 O 2 redox signaling is shown to directly increase mtROS production in one of the forms of ROS-induced ROS release ( DAMPs, particularly HMGB1, have been implicated in epilepsy pathogenesis

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318 Proteins that escape monitoring by the UPS can clump together, creating harmful substances that are difficult for the proteasome to break down and remove