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Alanine-based spacers promote an efficient antigen processing and presentation in neoantigen polypeptide vaccines
Leave-one-out analyses demonstrated stable results across outcomes
In: Reference Module in Biomedical Sciences
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Aliment Pharmacol Ther 2000
Compound 14 should be singled out from the others, since it shows good inhibitory activity (IC 50 = 3.56 M), which is almost 2.5 times more effective than allopurinol (IC 50 = 7.86 M), a drug that has already been consolidated in the treatment of hyperuricemia (Figure 7)
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