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The FDA has approved Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide) for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, when used with a reduced-calorie diet and increased physical activity
PNAS Nexus 5 , pgag171 (2026)
Only three semaglutide drugs are approved by the FDA, including Ozempic, Wegovy, and Rybelsus, while in India, the Drugs Controller General of India (DCGI) has approved only Novo Nordisk's oral semaglutide (Rybelsus)
Alternate Dosing Schedules : For long-term users with stable results, dosing frequency may be reduced (e.g., biweekly injections at the same dose)
To stay safe, talk to your healthcare provider about your options and consider lifestyle changes that support healthy digestion