Key Benefits: Helps in nerve regeneration and reduces neuropathic pain
I have shared my response below
The drug companies believe that hitting more receptors induces better weight-loss effects, which does appear to be true, but when it comes to what this is doing across different immune populations, downstream signaling can be completely changed by adding on these extra agonists, she says
At the adipose tissue level, the combined GIP and GLP-1 agonism reduces M1 macrophage infiltration and pro-inflammatory cytokines such as leptin, increases adiponectin, and enhances insulin sensitivity, thereby improving adipocyte dysfunction.39 GIP additionally increases the storage capacity of adipose tissue, which lowers the likelihood of ectopic fat deposition and reduces the extent of visceral fat.1,5,39 Furthermore, it has demonstrated neuroprotective effects and promotes bone formation1 (Table 2)
GLP-1 receptor agonists have demonstrated sustained weight loss of 15-22% in clinical populations, yet many people face monthly bills exceeding $900 for brand-name versions
These options will ultimately be discussed with the provider once your weight loss goal is achieved