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[1] Other rare side effects noted (mostly in older literature or high-dose use) include: polycythemia vera and peripheral vascular thrombosis in patients receiving repeated injections (though these associations are not well understood, they were listed in prior product literature as possible adverse events)
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Pen Dosage Chart Dosage & Protocols Variations Standard Research Protocol Dose: 5 10 mg daily (= 1530 clicks) Duration: 2 4 weeks Frequency: Daily Cycle Interval: 2-week pause Goal / Description: For baseline NAD+ and fat metabolism studies
However, it has been recently described that mTORC2 also possesses tyrosine phosphorylation capacity [118], and that it phosphorylates tyrosines on IRS and tyrosine kinases in both receptors, IGF-1 and IR, thus reinstituting the signal of the activated receptors [118]