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Although these drugs are intended for long-term use, real-world discontinuation rates are high 39% go off the meds within three months and 50% within 12 months

Liraglutide (the active ingredient in Saxenda and Victoza) and semaglutide (the active ingredient in Ozempic) are two of the most studied options, and while they work through the same pathway, they differ in dosing, potency, side effects, and the kind of support they offer over time

Comparison with other weight loss medications Semaglutide is unique compared to other weight loss medicines