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Regarding the mentioned studies, it seems that a higher dosage of folic acid especially in combination with B6 and B12 could alleviate the symptoms of migraine

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A recent review of curcumins distribution reported that although curcumins tissue distribution has been extensively studied in rats, evaluations in humans are limited (71)

Note, the occlusion/occlusion-like syndromes [18,19,20,21,22,23,24,25,26,27,28,29,30] include, permanent major vessel occlusion or permanent compression