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454 However, the IMpassion030 trial failed to demonstrate the efficacy of adjuvant atezolizumab in combination with chemotherapy

Vaughan RA, Garcia-Smith R, Bisoffi M, Trujillo KA, Conn CA (2012) Effects of caffeine on metabolism and mitochondria biogenesis in rhabdomyosarcoma cells compared with 2,4-dinitrophenol

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The daily dose can then be adjusted based on individual blood glucose targets